Multiple Sequence Alignment Averaging Improves Phylogeny Reconstruction
نویسندگان
چکیده
منابع مشابه
HandAlign: Bayesian multiple sequence alignment, phylogeny and ancestral reconstruction
UNLABELLED We describe handalign, a software package for Bayesian reconstruction of phylogenetic history. The underlying model of sequence evolution describes indels and substitutions. Alignments, trees and model parameters are all treated as jointly dependent random variables and sampled via Metropolis-Hastings Markov chain Monte Carlo (MCMC), enabling systematic statistical parameter inferenc...
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With the advent of next generation sequencing technologies, alignment and phylogeny estimation of datasets with thousands of sequences is being attempted. To address these challenges, new algorithmic approaches have been developed that have been able to provide substantial improvements over standard methods. This paper focuses on new approaches for ultra-large tree estimation, including methods...
متن کاملMultiple Sequence Alignment Multiple Sequence Alignment
An algorithm for progressive multiple alignment of sequences with insertions " , 1. Introduction The problem of sequence alignment is to find the patterns of sequence conservation and similarity between pairs or sets of given sequences. In biological contexts, similarity between biological sequences usually amounts to either functional or structural similarities or divergence from a common ance...
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Preface Since the identification of DNA/RNA as genetic material, deciphering the code of life has been a major goal put forward by biologists. One approach particularly successful in studying DNA sequences is to compare related sequences from different organisms. Sequence alignment, specifically pairwise alignment, is among the earliest tool developed in bioinformatics. However, the generalizat...
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ژورنال
عنوان ژورنال: Systematic Biology
سال: 2018
ISSN: 1063-5157,1076-836X
DOI: 10.1093/sysbio/syy036